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Dr.V.M.Chandrashekhar
Department of Pharmacology
Research M.Pharm projects: 15
Evaluation of cardiaoprotective activity of Abutilon indicum in albino rats-2007.
Hepatoprotective activity of Stereospermum suaveolens on Albino rats- 2007.
Antiosteoporotic effect of Berberis aristata on ooveriectomized rats-2007.
Neuroprotective activity of Matricaria recutita in oxidative stress induced rat model - 2007.
Evaluation of anti-arthritic activity of Indicofera tinctoria in albino rats - 2008.
Pharmacodyanamic and Pharmacokinetic Drug-Drug interaction of Osemoprazole with anti-diabetic agents-2008.
Evaluation of anti cancer activity of Moligno olifera on EAC bearing mice- 2008.
Pharmacodynamic interaction of xanthine oxidase inhibitors with piracetamin and quercetin in ischemia /reperfusion induced oxidative stress-2008.
Evaluation of Quinazolinone derivatives as potential anti-inflammatory and anti-arthritic activity agents- 2009.
Neuroprotective activity of Sterosperum suvelolens DC. against global cerebral ischemia and Parkinson’s disease in rat model-2009.
Evaluation of anticancer activity of Marine Zoanthus Spp.in EAC bearing mice-2009.

Antigenotoxic effects of Chamomile tea and Black tea against cyclophosphamide inducing genotoxicity in swiss albino mice

Pharmacological studies on Matricaria recutita L. in acute and chronic inflammation.
Neuroprotective activity of Berberis aristata DC against Global cerebral ischemia and Parkinson’s disease in rat model.
Evaluation of anti-osteoporosis activity of marine Zoanthus Sp.on SD rats.
   
 

Publications: Papers published in International and National scientific Journals: 23

   
P.M. Santosh, M.H. Shalavadi, V.M. Chandrashekhar and K.D. Vinay. Neuroprotective Activity of Valeriana officinalisagainst Global Cerebral Ischemia/Reperfusion Induced Oxidative Stress in Rat. Pharmacologia. 2015; 6 (8): 421-429, 2015
A Trivedi, HR Katti, MH Shalavadi, A Ramkishan, VM Chandrashekhar. Anti-osteoporotic activity of ethanol extract of Terminalia arjuna (Roxb.) Wight & Arn. on ovariectomized rats. Indian Journal of Natural Products and Resources. 2015;6(2):98-105.
R G Kulkarni, S Laufer, C V Mangannavar, A Garlapati. Design, Synthesis and Characterization of N', N”-Diaryl Ureas as p38 Kinase Inhibitors. Medicinal Chemistry. 2013; 9 (2),; 213-221.
Raghavendra P. Bakale, Ganesh N. Naik, Chandrashekhar V. M, Iranna S. Muchchandi, I. N. Shcherbakov, Chris Frampton, Kalagouda B. Gudasi. Mixed ligand complex via zinc(II)-mediated in situ oxidative heterocyclization of hydrochloride salt of 2-chlorobenzaldehyde hydralazine hydrazone as potential of antihypertensive agent. European Journal of Medicinal Chemistry. 2014;73: 38-45.Impact factor: 3.447
VM Chandrashekhar, S Ganapaty, A Ramkishan, ML Narsu. Neuroprotective activity of gossypin from Hibiscus vitifolius against global cerebral ischemia model in rats. Indian Journal of Pharmacology. 2013; 45 (6); 575.
Alkesh Patel, S. Rajesh, V.M. Chandrashekhar, Shivprakash Rathnam, Karishma Shah, C. Mallikarjuna Rao, K. Nandakumar. A Model against chemotherapy plus radiation –induced oral mucositis. Sudi Pharmaceutical Journal. 2013; 21 (4);;399-403. Impact factor: 0.954 Impact factor: 1.283
M. H. Shalavadi, V. M. Chandrashekhar, A. Ramkishan, R. B. Nidavani, and B. S. Biradar. Neuroprotective activity of Stereospermum suaveolens DC. against ischemia/reperfusion induced oxidative stress in rat. Pharmaceutical Biology. 2013; 51 (8): 995-960. Impact factor: 1.241
Ravindra G. Kulkarni, Stefan Laufer, Chandrashekhar V.M, Achaiah Garlapati. Design, Synthesis and Characterization of N', N”-Diaryl Ureas as p38 Kinase Inhibitors. Medicinal Chemistry, 2013; 9;2:213-221.Impact factor:1.496
Ravindra G. Kulkarni, Stefan A. Laufer, Chandrashekhar V. M and Achaiah Garlapati. Synthesis, p38 Kinase Inhibitory and Anti-inflammatory Activity of New Substituted Benzimidazole Derivatives. Medicinal Chemistry. 2013; 9;1:91-99. Impact factor:1.496
Madhusudan N. Purohit, V. M. Chandrashekhar, Y. C. Mayur. Synthesis and in vitro Cytotoxicity Studies of Certain Novel Heterocycles Derived from Bis 1, 2, 4-Triazoles and their DNA Damage Studies. Medicinal Chemistry, 2013 [ARTICLE IN PRESS]. Impact factor:1.496
Rohit Singh, Gurubasavaraj V. Pujar, Madhusudan N. Purohit, V. M. Chandrashekar.Synthesis, in vitro cytotoxicity, and antibacterial studies of new asymmetric bis-1,2,4-triazoles. Medicinal Chemistry Research. 2012 [ARTICLE IN PRESS] DOI:10.1007/s00044.012.0209-5. Impact factor:1.271
Shalavadi M.H., Chandrashekhar V.M., A.Ramkishan, Deepak Biswas, Raju Biradar. Neuroprotective activity of Stereospermum suaveolens DC. against ischemia/reperfusion Induced oxidative stress in rat. Pharmaceutical Biology;2013;51 (8);955-960.Impact factor:1.241
Shalavadi M.H., Chandrashekhar V.M., A.Ramkishan, Avinash S.P , Sowmya C. Neuroprotective activity of Stereospermum suaveolens DC. against 6-OHDA induced Parkinson’s disease model. Indian Journal of Pharmacology; 2012;44 (6):735-743. ;Impact factor: 0.727
Dayananda S. Badiger, Rekha S. Hunoor, Basavaraj R. Patil, Ramesh S. Vadavi, Chandrashekhar V. Mangannavar, Iranna S. Muchchandi, Kalagouda B. Gudasi. Synthesis, physico-chemical characterization and antimicrobial activities of 3-methoxysalicylaldehyde-2 aminobenzoylhydrazone and its transition metal complexes. Journal of Molecular Structure. 2012,1019,159–165: Impact factor: 1.601
V.M. Chandrashekhar, Nirav M. Patel, R.B. Nidavani, Jignesh N. Vadiya and S. Ganapaty, Anti-ischemic Effect of German Chamomile (Matricaria recutita L.) Against Ischemia/reperfusion Induced Myocardial Damage in Isolated Rat Heart. Pharmacologia. 2012, 3: 406-412
Dayananda S. Badiger, Ramesh B. Nidavani, Rekha S. Hunoor, Basavaraj R. Patil, Ramesh S. Vadavi, V. M. Chandrashekhar, Iranna S. Muchchandi and Kalagoud B. Gudasi. Transition metal complexes of 1,2-dihydroquinazolinone derivative, an emerging class of analgesic and anti-inflammatory agents. Appl. Organometal. Chem. 2011, 25, 876–882: Impact factor: 2.242
Dayananda S. Badiger, Rekha S. Hunoor, Basavaraj R. Patil, Ramesh S. Vadavi, Chandrashekhar V. Mangannavar, Iranna S. Muchchandi, Yogesh P. Patil, Munirathinam Nethaji, Kalagouda B. Gudasi, Synthesis, spectroscopic properties and biological evaluation of transition metal complexes of salicylhydrazone of anthranilhydrazide: X-ray crystal structure of copper complex. Inorganica Chimica Acta; 2012; 338; 197-203. Impact factor: 2.046
V.M. Chandrashekhar, K.S. Halagali, R.B. Nidavani, M.H. Shalavadi, S. Ganapaty, D. Biswas and I.S. Muchchandi. Anti-allergic activity of German chamomile (Matricaria recutita L.) in mast cell mediated allergy model. Journal of Ethnopharmacology, 2011. 1; 137(1):336-40. Impact factor:3.014
Ashok A.Muchnadi,V.M.Chandrashekhar. Antiulcer and gastroprotective potential of Stereospermum suaveolens in Wistar rats. Journal of Pharmcology and Pharmacotherapeutics . 2011.2 (3),117-119.
AshokA. Muchandi, V.M.Chandrashekhar. Evaluation of hepatoprotective and antioxidant activity of Stereospermum suaveolens against aluminium fluoride induced hepatotoxicity. Journal of Natural Remedies (JNR). 2011; 11(2),143-149.
Rekha S. Hunoor, Basavaraj R. Patil, Dayananda S. Badiger, Ramesh S.Vadavi, Kalagoud B. Gudasi,, V.M. Chandrashekhar and I. S.Muchchandi. Synthesis, characterization, anti-inflammatory and analgesic activity of transition metal complexes of 3-[1-(2-hydroxyphenyl) ethylideamino]-2-phenyl-3, 4-dihydroquinazolin-4(3H)-one. Appl. Organometallic Chemistry. 2011, 25(6), 407-485. Impact factor:3.014
V.M.Chandrashekhar, Prasahant D.Phadatare,. Influence of esomeprazole on hypoglycemic activity of oral anti-diabetic agents in rats and rabbits. Molecular and Cellular Biochemistry, 2011, 354, 135-140. Impact factor:2.057
H.S.Yogesh, V.M.Chandrashekhar, H.R.Katti, S.Ganapaty, H.L. Ragavendra, Giresh.K.Gowda, B.Goplakrishna. Anti-osteoporotic activity of aqueous- methanol extract of Berberis aristata in ovariectomized rats. Journal of Ethnopharmacology, 2011,134, 334-338. Impact factor:3.014
Vishawas L.Ranpariya, S.K.Parmar, N.R.Seth, V.M.Chandrashekhar, Neuroprotective activity of Matricaria recutita against fluoride induced stress in rats. Pharmaceutical Biology 2011; 49(7): 696–701. Impact factor: 1.241
Rekha Shankar Hinoor, Basavaraj Rudragouda Patel, Dayananda Shivappa Badiger, Ramesh Shivananadappa Vadavi, Kalagouda Basappa Gudasi, Chandrashekhar Venkaraddi Magannavar, Irran Sangappa Muchandi. Spectroscopic, magnetic and thermal studies of Co(II), Ni(II),Cu (II) and Zn (II) complexes of 3-acetylcoumarin-isonicotinoylhydrazone and their antimicrobial and anti-tubercular activity evaluation. Spectrochemica Acta Part A. 2010; 77, 838-844. Impact factor: 2.098
V.M.Chandrashekhar, V.L..Ranpariya, S.Ganapaty, A.Parashar, A.A.Muchandi. Neuroprotective activity of Matricutita recutita in global ischemia model. Journal of Ethinopharmacology, 2010, 127, 3, 645-65. Impact factor:3.014
S.Ganapaty, V.M.Chandrashekhar, M.Laxim Narasu. Antiallergic activity of gossypin and suramin in allergic model. Journal of Biochemistry and Biophysics, 2010;47, 90-95 : Impact factor: 1.142
Chandrashekhar.V.M, A.Muchandi, Sarasvathi Sodi, Ganapaty, S. Hepatoprotective activity of Stereospermum suaveolens DC against CCl4–induced hepatotoxicity. Pharmaceutical Biology, 2010; 48 (5), 524-528. Impact factor: 0.878
H.R.Chitme, Mallikarjun Malipatil, V.M.Chandrashekhar, P.M.Prashant. Anti-allergic activity of Aristiolochia bracteolate Lank in animal model. Indian Journal of Experimental Biology, 2010; 48, 46-52. Impact factor: 1.295
S.Ganapaty, V.M.Chandrashekhar, H.R.Chitme, M. Laxmi narsu, Free radical scavenging activity of gossypin and nevadensin: An in-vitro evaluation, Indian Journal of Pharmacology, 2007; 39 (6), 281-283. Impact factor: 0.727
Rekha Shankar Hinoor, Basavaraj Rudragouda Patel, Dayananda Shivappa Badiger, Ramesh Shivananadappa Vadavi, Kalagouda Basappa Gudasi, Chandrashekhar Venkaraddi Mangannavar, Irran Sangappa Muchandi. A study of Ant-inflammatory and analgesic activity of New 2,3-Disubstituted 1,2-Dihydroquinazolin-4(3H)-one Derivative and its Transition Metal Complexes. Chem. Pharm. Bull, 2010; 58 (5), 7122-716. Impact factor: 1.70
Raghavendra Hl, Yogesh HS, Gopalakrishna B, Chandrashekhar VM, Sathish Kumar BP, Vadlapuri Kumar. An overview of Herbal medicine. International Journal of Pharmaceutical Sciences, 2009;1,(1), 1-20.
Madan Kaushik, MuchchandiI. S., Chitme H. R, Chandrasheker V. M. Effect of Ficus Glomerata Roxb Latex on behavioural of adjuvant-induced arthritic rats. Journal of Chemical and Pharmaceutical Sciences, 2009; 2 (3), 172-175
Y.Srinivas, V.M.Chandrashekhar, I.S.Muchachandi, B.S.Kittur. Anti-inflammatory Activity of Ficus glomerata Roxb latex against carrageenan induced rat paw edema in rats. Pharmacologyonline 2: 963-966 (2009)
Chandrashekhar.V.M, Muchandi.I.S, Sarasvathi.V.Sodi, Muchandi I.S. Free radical sacvenging activity of Stereospermum suaveolens DC: An in vitro evaluation. Pharmacologyonline, 2009.1, 50-56
Abstract Published: Masood MK, Sudi SV, Birade Deepa., Patel AK, Muchandi I.S, Chandrashekhar VM. Anticancer activity of Strychnos potatorum Linn, on EAC induced female Balb/C mice. Indian Journal of Pharmacology, 2009; 41, 1. Impact factor: 0.727
Abstract Published: Patel NM, Prasher A, Ranpariya V, Vadiya JN, Reddy S, Chandrashekhar.VM. Cardiprotective activity of Abutilon indcum Linn in swimming induced cardiac hypertrophy in albino rats. Indian Journal of Pharmacology, 2009; 41, 1. Impact factor: 0.727
   
  Presentations in International/National Conferences/Seminars/Symposium: 32

International Conferences : 07
   
V.M.Chandrashekhar, Mallappa Shivadi, Deepa.S.Birade, Ramesh. B. Nidavani. Neuroprotective activity of Stereospermum suaveolens agonist global and 6-OHDA induced Parkinsonism model. Invited speaker, Third International Conference on Natural Products for Health and Beauty Bangkok, Thailand, March 16-18, 2011
Raghavendra H.L, Maitree Suttajit, Vidhya Ramaswamy, Chandrashekhar V.M, Vadlapudi Kumar. In vitro antidiabetic, antioxidant and antilipidimic activity of a new phytochemical combination. Third International Conference on Natural Products for Health and Beauty Bangkok, Thailand, March 16-18, 2011-Oral presentation
Deepa. S. Birade, Chandrashekhar V.M, Raghavendra H.L, Chandraraj. C. Simpi, Mrutyunjay Bellad, Dipak Biswas1 and B.S. Biradar1 Raju. Anticancer Activity of Marine Zoanthus species on Ehrlich Ascites Carcinoma Bearing Female Balb/c Mice. Third International Conference on Natural Products for Health and Beauty Bangkok, Thailand, March 16-18, 2011-Poster
V.M.Chandrashekhar,, S.Ganapaty, Laximi Narsu. Neuroprotective activity of natural products agonist ischemia/reperfusion induced oxidative stress. Was presented, 27-30th September at Chile, South American, for International conference on Free radical and antioxidant Chile 2009.
Raghavendra H.L, Maitree Suttaji, Chandrashekhar.V.M, Vadlapudi Kumar. Phytochemical Combination Regulates Carbohydrate Metabolism and Improves Antioxidant Status in Streptozotocin Induced Diabetes Mellitus. Third International Conference on Natural Products for Health and Beauty Bangkok, Thailand, March 16-18, 2011-Best Poster Awarded (First Prize).
Vishavas Ranpria,, ////////////////////// Neuroprotective activity of natural products agonist ischemia/reperfusion induced oxidative stress. Was presented, USA. (Accepted for presentation)
V.M. Chandrasekhar, A.N. Nagappa. Antidiarrhoeal activity of Abutilon indicm Linn in Albino rats, International conference, FAPA, Sydney (Australia), 27th to 30th October 2000.
   
  National Conferences/ Seminars
   
V.M.Chandrashekhar, S.Ganapaty, Laxmi Nasu. Antiallergic activity of gossypin and suramin , Poster presentation at International Conference on “Advances in Free Radical Research: Natural Products, Antioxidants and Radioprotectors” (AFRR – 2009) 8th Annual Meeting of the Society for Free Radical Research – India will be held during March 19-21, at the Scientific Convention Centre, C.S.M. Medical University, Lucknow, India. 2009.
Masood MK, Sudi SV, Birade Deepa., Patel AK, Muchandi I.S, Chandrashekhar VM. Anticancer activity of Strychnos potatorum Linn, on EAC induced female Balb/C mice. Indian Journal of Pharmacology, 2009, 41, 1. (Presented at Annual Conference of Indian Pharmacological Society, Dec 10-12, 2009, Kolkata, India.
Patel NM, Prasher A, Ranpariya V, Vadiya JN, Reddy S, Chandrashekhar.VM. Cardiprotective activity of Abutilon indcum Linn in swimming induced cardiac hypertrophy in albino rats. Indian Journal of Pharmacology, 2009, 41, 1. (Presented at Annual Conference of Indian Pharmacological Society, 2009, 10-12, Kolkata, India
Ashok A. Mucahndi, Ashish Prasher, I.S.Mucahndi, V.M Chandrashekhar. Anticancer activity of Cynodon dactylon on Swiss mice. Presented at National Level student’s Symposium, Basaveshwar Engineering College, Bagalkot, Karnataka, 21-22 Oct 2008.
Yogesh HS, Shombu Kichadi, I.S.Muchndi, V.M Chandrashekhar. Evaluation of anti-diabetic and nephroprotective activity of Indigofera tinctoria in experimental animals. Presented at National Level student’s Symposium, Basaveshwar Engineering College, Bagalkot, Karnataka, 21-22 Oct 2008.
Sarasvathi.V.Sudi, Nitin P.Patil, V.M.Chandrashekhar, H.R.chitme, I.S.Muchandi, Antiarthritic potential of Aristolochia bracteata R in albino rats, National Seminar, Current trends in Preclinical and clinical validation of Traditional medicines,18th -19th August Bagalkot, 2007.
Shambhu .C. Kichadi, Nitin P.Patil, V.M.Chandrashekhar, H.R.chitme, I.S.Muchandi, Analgesic and anti-inflammatory activity of Aristolochia bracteata R, National Seminar, Current trends in Preclinical and Clinical validation of Traditional medicines,18th -19th August Bagalkot, 2007.
Vishavas L. Ranpariya, V.M.Chandrashekhar, H.R.chitme, I.S.Muchandi, Transgenic animals and their application in Bio medical research, at National Seminar, Current trends in Preclinical and Clinical validation of Traditional medicines,18th -19th August Bagalkot, 2007.
Ashok A.Muchandi, V.M.Chandrashekhar, H.R.Chitme, I.S.Muchandi, Alternative to laboratory animal Experimentation (In Preclinical Study) , at National Seminar, Current trends in Preclinical and Clinical validation of Traditional medicines,18th -19th August Bagalkot, 2007.
Prashanath P.M, Chandrasekhar. V. M., I.S. Muchandi, H.R.Chitme. In-vivo and in vitro antiallergic activity of Aristolochia bracteata in compound 48/80 induced mast cell degranulation.at South Indian Pharmacological Society, South regional Conference, 12th -13th July, Pandichery, Andhra Pradesh.2006
Azamath.U.M, Chandrasekhar. V. M, Muchandi I.S, H.R.Chitme. Anticancer activity of Candydon dacitlon EAC induced carcinoma mice. at South Indian Pharmacological Society, South regional Conference, 12th -13th July, Pandichery, Andhra Pradesh.2006
V.M.Chandrashekhar, H.R.Chitme, N.R.rathod, I.S.Muchandi, Pharmacological evaluation of Wrightia tintoria (Roxb) R.Br. In albino rats. National Seminar on Emerging Trends in Ethnopharmacology, Bagalkot, 2005
Nanu rathod, M.S.Harish, Shubha hedge, V.M. Chandrasekhar, H.R.Chitme, I.S.Muchandi, Pharmacogical evaluation of immunostimulant activity of stimune polyhedral formulation, National seminar on Emerging Treads in ethanopharmacology, Bagalkot, 2005.
Umesh patil, R.Chanshetty, M.H.Patil, V.M.Chandrashekhar, I.S.Muchandi Antidiarrhoeal activity of Carrisa carrandas Linn root extract, National Seminar on Emerging Trends in Ethanopharmacology, Bagalkot,2005
V.M .Chandrasekhar, I.S.Muchandi, Y.Srinivas, AN..Nagappa Antidiarrhoeal activity of Hibiscus esculentus Linn in Albino rats,. In 54th Indian Pharmaceutical Congress, Pune, December 13,14 and 15, 2002
   
  National/International Conferences/Seminars/Symposium Etc., Attended
   
Thailand
International conference Free radicals and antioxidant, SFRB South American group, at Chile, South America (2009).
Advances in Free Radical Research: Natural Products, Antioxidants and Radioprotectors” (AFRR – 2009) 8th Annual Meeting of the Society for Free Radical Research – India will be held at the Scientific Convention Centre, C.S.M. Medical University, Lucknow, India (2009)
South Regional Indian Pharmacological Society, Puduchery ( 2008)
55nd Indian Pharmaceutical Congress, Chennai (2003)
54nd Indian Pharmaceutical Congress, Pune (2002)
53rd Indian Pharmaceutical Congress, New Delhi (2001).
International convention of Pharmacy Educators on International Trends in Pharmaceutical Sciences and Practice, Bangalore (2002).
Annual National Convention (7th), APTI, Goa College of Pharmacy, Goa (2002).
8th Annual National Convention, APTI, KLE College of Pharmacy, Hubli, (2003)
 
   
 
 
 
 
   
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